Steve Croft, Ph. D. |
Interview with Art Wallace, MD PhD on Big Data and Medical Innovation
In the upcoming Marin Science Seminar, “Big Data and Medical Innovation,” Dr. Art Wallace, Chief of Anesthesia Service at the San Francisco VA Medical Center and a Professor of Anesthesiology and Perioperative Care at UCSF Medical Center, will discuss applications of Big Data in medicine and how Big Data has changed epidemiology, quality improvement, and drug discovery. Read the following interview to learn more about Dr.
Wallace’s thoughts on Big Data and its impact on medical innovation.
Art Wallace, MD PhD |
Interview with Alex Gunderson, Ph.D: The Price is Wrong
Interview with Alex Gunderson Ph.D.
by Isobel Wright, MSS Intern, Tamalpais HS
Alex Gunderson, Ph. D.
1. How did you decide to enter this line of work, as it is so specialized?
I think I gravitated toward biology as a profession because I love being in nature. I grew up in a very rural part of the Midwest where I spent a lot of time outside, on lakes and in the woods. That led me to be interested in how the natural world works.
2. Why did you decide to use the Price is Right as an analogy for the effects of global warming?
The Price is Right was as easy choice for me because it is one of my favorite game shows. When I was in grade school and would get sick and stay home, it was the show I looked forward to watching most. I have always wanted to spin the big wheel!
I have learned a lot! Maybe one of the biggest things is how subtle nature can be. On Puerto Rico there are ten different species of Anolislizard and to most people they all just sort of look like a generic lizard. But when you look closely, you see that they have evolved all of these small differences that allow them to live and thrive in different habitats. It really is amazing!
4. What level of education do you need to do what you do?
It depends on what your ultimate goal is. You can get paid to do biology with a Bachelor’s degree, but many positions require graduate degrees like a Master’s or PhD. My goal is to be a college professor, so a PhD is required.
5. If there was one thing you could tell us to do to prevent climate change, what would it be?
The biggest road-block to making progress on climate change is political inaction, so speak up about it through your vote (if you are 18!), letters to politicians, and outreach activities. On a personal level, there are a lot of things you can do to reduce your contribution to climate change. The Nature Conservancy has a great website where you can calculate your carbon footprint and learn about ways to reduce it: http://www.nature.org/greenliving/carboncalculator/
6. What was your biggest “Aha” moment in life so far, relating to your work?
I think the biggest “Aha” moment I had was when I decided that I wanted to study how animals adapt to different climates. It was my first year as a PhD student, and I was in Puerto Rico for the first time. I thought I wanted to study the evolution of animal signals, or how animals communicate with one another. I had been studying one species in northern Puerto Rico, but I knew the same species also lived in southern Puerto Rico so I decided to drive down there. I was driving south through the mountains with my cousin Neil (he was helping me do my research) and all of a sudden, the landscape changed dramatically. It went from cool, shady tropical rainforest to hot, dry desert in just a few miles. I thought there was no way the same species could live in such different conditions. But sure enough, the same species was there. I wanted to know how they did it, and my fascination with thermal biology was born!
7. What are the best parts of your job? What are the worst parts?
There are two things that I think are best about my job. First, my job takes me amazing places to study amazing animals. Over the years, I have studied lizards in the Caribbean, frogs in the back-country wilderness of Montana, and seabirds in the Galapagos, to name a few. Hard to beat. Second, in many ways, I am my own boss. With some caveats, I get to decide what I study, where I study it, and how I study it. That kind of freedom is hard to come by in many professions.
The worst part of my job? Writing grants. Because most scientific research doesn’t generate profits like a business, you have to convince other people to give you money to do it. Those “other people”are usually government agencies like the National Science Foundation and the National Institutes of Health. It’s fantastic that they give the money, but the grant writing itself is often extremely tedious.
Learn more about Alex Gunderson and his research here. Join us and Learn!
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Saving Our Ocean Friends: An Interview with Dr. Claire Simeone of the Marine Mammal Center
Claire Simeone, DVM |
Join us for “Sick Seals and Seizing Sea Lions: What Marine Mammals Can Tell Us About the Health of Our Oceans” with Claire Simeone DVM of The Marine Mammal Center, Sausalito – Wednesday, October 8th, 2014 at Marin Science Seminar
Mission Control with Jay Trimble
1. What are some of the projects that the User Centered Technology (UCT) Group at NASA Ames Research Center has worked on?
The UCT Group has focused on component software that allows users to build their own software with compositions, meaning users can essentially assemble their own software using drag and drop. The software is open source, it’s called Open Mission Control Technologies. You can learn more about the software at http://ti.arc.nasa.gov/
The process for making software is focused on the users. We use a range of methods to connect with users and translate what we’ve learned into the design of the software. We observe users doing their work in their own environment. This is important because observing users gives you a perspective that you won’t get by talking to them, though talking to users is also important. We interview users as well to better understand their work. We develop prototypes and iteratively improve them. Ideas are communicated and tested visually before committing to code.
For Mars Rover Operations we worked with the Jet Propulsion Lab (JPL). We were part of a team looking at science processes. We developed software that ran on large touch screens that allowed the scientists to plan several days out what they wanted to be doing.
My favorite parts of my job are being part of space exploration and the people I work with. My least favorite part of the job is the uncertainty of the federal budget process.
That’s a very broad question. My group is working on a Lunar Rover Mission to conduct surface exploration in polar regions to prospect for water and other resources. That’s our focus at the moment. We are also continuing to work with JPL on software for monitoring solar system exploration spacecraft. I think space technology in general in focused on moving us beyond low Earth orbit and out into the solar system.
I decided my career path based on my interest in the space program that began in grade school when we were landing on the Moon.
High Tech Mannequins
Abi Fitzgerald practices one day every week in the emergency department at the SFVA as part of her one year fellowship in advanced clinical simulation. She is an RN and achieved her MSN at San Francisco State University. Read the following interview with Abi Fitzgerald to find out more about her experience with the simulators!
The Adorable, Rewarding, and Sometimes Difficult Task of Birthing Babies
A common misconception is that the only job of a midwife is to deliver babies. In reality, the duties of a midwife begin long before the baby is born. A midwife can screen for diseases, prescribe certain
Matteo explained that midwifery in the U.S. has undergone many changes throughout history.
“Before the early 20th century, most babies in the US were delivered by midwives at home. Then
medicine, mostly male doctors, brought birth into hospitals and birth became a medical condition.
Women were put to sleep and babies were delivered with forceps. Moms were encouraged to bottle
feed. Midwifery pretty much vanished. In the 1970’s, with the rise of feminism and the “natural birth”
movement, midwifery as a profession started to grow again. Unlike many other industrialized countries
with better childbirth statistics where midwifery care is the norm, midwifery in the US has stayed on
the fringe and been seen as an “alternative” birth option. In the 15 years that I have been practicing,
I have seen many midwifery services grow and disband based on whatever economic issue was driving
healthcare at that time. Healthcare in the US is still largely driven by economics and legislation, but
midwives and other “mid levels” or “allied health professionals” are rising in use and stature. We
have rigorous education and certification maintenance programs and are fully integrated into healthcare
teams with nursing, case managers and social workers, as well as doctors. The profession is growing in
numbers and strength and our good outcomes are more commonly recognized by clients and medicine
professionals.” According to Time magazine, approximately 8% of babies born in the U.S. – a record
high – and about 24% of babies in New Mexico were delivered by midwives in 2009. While delivery in
the U.S. usually takes place in a hospital in the presence of obstetricians, more and more women are
turning to midwives.
Read the rest of the interview with Sheri Matteo for a sneak peek preview of her upcoming MSS
presentation “Birthing Babies: What it Takes to be a Nurse Midwife”.
For more information go to:
Our Bodies Ourselves Health Resource Center
Dimensions Healthcare System
Student Medics
Time Magazine
Image credits:
https://drewstarr.wordpress.com/pictures/early-american-midwifery/
http://www.sciencemuseum.org.uk/broughttolife/themes/birthanddeath/childbirthandmedicine.aspx
http://healthsciencetechnology.wikispaces.com/Midwife
http://firststepskent.org/welcome-home-baby/welcome-home-baby-book/
A Renewed Sense of Porpoise – An Interview with Jonathan Stern
Fast Fasts about the Harbor Porpoise from the National Geographic Society:
Terra Linda High School graduate Jonathan Stern is a lecturer and adjunct professor in the Biology Department at San Francisco State University. He has studied minke whales since 1980 and currently serves as a Co-Principal Investigator at Golden Gate Cetacean Research, where he studies harbor porpoises, bottlenose dolphins, and minke whales locally in the San Francisco Bay. He has also studied an assortment of whales including gray whales, killerwhales, fin whales, humpback whales, and pilot whales. He was the first volunteer at the Marine Mammal Center when it opened in 1975.
How did you decide to study marine life?
From left: Lloyd Bridges stars in Sea Hunt, Seashell collection, Explorer Jacque Cousteau |
How do you conduct your research?
Harbor Porpoise sighting near the Golden Gate Bridge |
Report your porpoise sightings! Golden Gate Cetacean Research’s page for Porpoise, Dolphins & Whale sightings in SF Bay & the NorCal coast. http://www.ggcetacean.org/
To learn more about the return of the harbor porpoise and its ecological implications, attend the Marin Science Seminar presentation “San Francisco Bay Has a Renewed Sense of Porpoise” with Jonathan Stern Ph.D. of San Francisco State University, January 29, 2014, 7:30 – 8:30 pm, Terra Linda High School, San Rafael, Room 207. See the flyer here
Want more information? Check out the websites below.
National Wildlife Federation California
Golden Gate Cetacean Research
National Geographic
NPR
SF Gate Article
~Claire Watry
A Behind the Scenes Look into the Lawrence Berkeley Lab with Polite Stewart
What makes Polite (pronounced “po-leet”) Stewart stand out from any other person working in the Advanced Light Source department at the Lawrence Berkeley Lab? The answer is that Polite is only nineteen years old. His remarkable story begins with a young boy who has a knack for learning.
- Postbac – Post Baccalaureate (a college level degree)
- ALS – The Advanced Light Source is a specialized particle accelerator that generates bright beams of x rays for scientific research. [2]
- How the ALS works – Electron bunches traveling nearly the speed of light, when forced into a circular path by magnets, emit bright ultraviolet and x-ray light that is directed down beam lines or tubes to different research labs. [2]
- How Bright Is It? – The ALS produces light that is one billion times brighter than the sun. This tool offers research in materials science, biology, chemistry, physics, and the environmental sciences.
- My interest in physics is related to kinetics (motion) Newtonian physics, and that interest was piqued because I knew it would be useful to know about force transmission in the martial arts. It also helped me gain a better understanding of mathematics, engineering, and chemistry via research and self-study; everything is connected. My true interest is bio-engineering. I plan to research neuro-muscular theory to help people improve and repair lost neuron connection.
- At the moment, I work with hard X-Ray Scattering, specifically Small-Angle(SAXS) and Wide-Angle(WAXS). X-ray scattering is an analysis technique that uses x-rays to determine the structural formation of an object. At my beam line, 7.3.3, we specialize in protein, block co-polymer, polymer, and semi-conductor based samples. Transmission SAXS/WAXS is used to view a sample’s interior; whereas, Grazing Incidence(GISAXS/GIWAXS) is used to look at the surface structure of a sample.
- A synchrotron is a huge particle accelerator that uses magnets to control electron bunches. The electron bunches are what make up the particle beam that each beam line end station (workplace) uses. The particle beam at our synchrotron is only a few micrometers wide and over 10x brighter than the sun.
- Well, that has a very long answer. The simplest answer would be to state that the aforementioned electron bunches are necessary to irradiate samples and therefore extract data…but, let’s go deeper than that. First, a synchrotron is a just another version of the particle accelerator. So, we must determine why a particle accelerator is useful. Fundamentally, it is known that everything in this world is made up of atoms and molecules. There are smaller particles but we will only concern ourselves with the structures, for now, and not their components. Atoms and molecules are, of course, too small to see with the naked eye so, in essence, particle acceleration is our window into the world of the micro- and nano-structures.
- How does this work? The electron bunches are sped up to a very high constant speed and then the bunches are sent down each individual beam line’s lead tunnel. The light is then rammed into your sample. When this occurs, the electrons in the beam will then collide with atomic and molecular structure of your sample. This will cause photons (light emission from the bouncing of electrons in particle space) to be emitted. This emission is then recorded and visualized as a scattering profile. This means that a synchrotron is very useful for allowing us to see the unseen. It is one of the many windows that helps us to understand the results of biology, chemistry, and engineering as a whole.
- This research has only one real goal. It is to speed up the progress of science. At the synchrotron, there is something called beamtime. Beamtime is the experiment time given to each scientist who writes a proposal to use our beam line. This implies that many research groups frequent our beam line and the synchrotron itself. My job, and my employers’, is to aid in the experimentation process. This increases (research) paper output, which in turn increases the output of scientific knowledge, and eventually improves consumer life (i.e. you).
- The research that we do at the Advanced Light Source (ALS) is designed to help the commercial (consumer) and financial (business) sectors because helping the commercial automatically helps the financial.
- I have two jobs as a student researcher on the beam line: help the users (various research groups) at the beam line and write programs/make changes to enhance, and increase the efficiency of, the beam line. User assistance only lasts as long as the given research group’s experiments. On the other hand, enhancement of the beam line will never stop.
- There is no such thing as a typical day, but I would say days normally start off with determining whether users are present. If they are, the whole day is generally devoted to helping them with experiment setup and execution. If there are no users, then the morning might be spent cleaning the beam line and the remaining afternoon would be devoted to programming.
- Currently, I see myself working for another year. Hopefully, it will be with Lawrence Berkeley Lab in the life sciences department. If not, I will apply to other labs and try to get a biological position. In the future, I would like to get a Masters in Bio-Engineering, possibly from Berkeley, and then go overseas to get my PH.D. and do my post-doc in Japan.
- This is a difficult question. The first step is to cultivate and maintain a self-driving spirit and will. From a different take, I’m saying that, first and foremost, the level to which you want to learn determines how much you learn. Effort and excellence are proportional; even you don’t see the results immediately.
- Now that effort has been determined as the essential element, let us discuss the limiting factor: resources. Resources (lab equipment and opportunities) are hard to acquire and difficult to locate. However, there is a hack…and then there’s a cheat code. I know they sound the same but they most certainly are not. The cheat code are summer programs. Look up as many as you can, find the ones that interest you, and apply with all the initiative you can possibly muster.
- Finally, the hack is the ability to network. How do you develop this hack? Talk to anyone and everyone who gives off a positive light. In school, on the street, in the store, at home, and especially at a place you would love to work at in the future. The key to your success is your voice and your ability to use it. When you see a person who could benefit you, address him/her, introduce yourself, and begin to discuss how you could help them and they can help you. Only practice can make you adept at communication, but once you can talk with poise and demonstrate mental rigor…there will be no limiting you or the passion which you hold in your heart.
- http://www.marinscienceseminar.com/speakers/pstewart.html
- http://www.huffingtonpost.com/2012/12/17/polite-stewart-18-year-old-physics-major-bachelors-degree-southern-university_n_2315446.html
See the flyer for Polite’s upcoming presentation here.
Public Health Plays More Roles In Your Life Than You May Think
When you hear the term public health, ideas that may come to mind might be about immunizations or food recalls. However, many of us don’t realize how big of a role public health plays in our everyday lives. From the faucets that we fill our drinking cups with to the seat belts that we wear in our cars, almost all aspects of our well being relate to Public Health in some way. On October 16th, 2013 Julie Pettijohn did an exemplary job of explaining the topic of public health and talked about what being in the field really involves. As an industrial hygienist, a typical work day for Julie is not just filling out paperwork in an office. Wearing a full outfit of protective gear, Julie often goes to a site to detect possible lead amounts in a work environment. Her job keeps us safe by enforcing the proper health requirements. The work and service of people like Julie in the public health field may often be taken for granted. Nevertheless, by attending the seminar many of us learned that being in the field is not just a job, it is establishing safe and healthy ways of life. I had the honor of asking Julie some questions about both herself and her field. Our interview is below.