Finding and Fighting Cells that can Kill us: One Patient’s Story

with Bradley Stohr MD PhD of UCSF

WHEN?: Wednesday, November 20th, 2024 – TLHS Innovation Hub – 7:30 – 8:30pm

Description: We humans are extraordinarily complex organisms, each of us composed of roughly 30 trillion cells. Our health depends on all of those cells working together in harmony, and just one cell going rogue can potentially spell disaster. In this session, Bradley Stohr of UCSF will share one patient’s story of battling a deadly disease. We’ll discuss how the cells that cause disease can be identified, how doctors can fight back against those cells, and why our best efforts are unfortunately not always enough.

Bradley Stohr MD PhD

Bio: Bradley Stohr MD PhD is Professor and Vice Chair in the Department of Pathology at University of California, San Francisco. He received a bachelor’s degree in Biology from Swarthmore College in 1995 and completed the Medical Scientist Training Program at Duke University in 2003. He has been in the Department of Pathology at UCSF ever since, first as a medical resident and fellow and then as a faculty member. He ran a basic science laboratory for many years but now primarily focuses his efforts on clinical practice (with expertise in genitourinary pathology) and as one of the primary administrative leads for his department.

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We Need New Antibiotics – Why Do We Have So Few?

with Julia Schaletzky Ph.D. of the Center for Emerging and Neglected Diseases and the Drug Discovery Center at UC Berkeley

Wednesday, November 1, 2023, Terra Linda High School Innovation Hub

Center for Emerging and Neglected Diseases
Center for Emerging and Neglected Diseases

Description: Antibiotics are one of the triumphs of science and we have become used to them as “silver bullets”, fighting potentially life-threatening infections. As drug-resistant pathogens continue to emerge, what are our options? Why are so few new antibiotics being developed and how do we have to think about the market-driven model of drug development in this context? Dr. Schaletzky will provide an overview about chemistry, discovery/development, overuse and the economics of antibiotic development, and discuss potential solutions to a problem that should be on everyone’s mind.

Bio.: Dr. Julia Schaletzky is the Executive Director of the Center for Emerging and Neglected Diseases and the Drug Discovery Center at UC Berkeley. After studying biochemistry in her native Germany, she moved to Harvard Medical School for graduate school. Interested in applied science, Dr. Schaletzky joined a biotechnology company, Cytokinetics, to develop new therapies for heart disease and neurodegenerative disorders, with several molecules in late-stage clinical trials. In her role at UC Berkeley, she focuses on interdisciplinary approaches and public/private partnership for the discovery and development of new therapies and tools, particularly for unmet medical needs. Dr. Schaletzky is also is a lecturer at the Haas School of Business, teaching Bioentrepreneurship, Access to Medicines and Drug Development for Neglected Diseases. She has received NIH-funded grants to support underrepresented minorities and women in STEM in the U.S. and runs a program in Uganda to build local research capacity. Dr. Schaletzky is broadly interested in global public health, bioethics, and the governance of processes that end up influencing who gets care and who does not.

Julia Schaletzky Ph.D. of the Center for Emerging and Neglected Diseases and the Drug Discovery Center at UC Berkeley
Julia Schaletzky

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Machine Vision for Medical Monitoring

with Art Wallace M.D. Ph.D. of the San Francisco VA Medical Center and UCSF Medical School

Wednesday, April 26, 2023 7:30-8:30pm, Terra Linda High School Innovation Hub

Touchless Medical Monitoring

This presentation will discuss the use of artificial intelligence and machine vision to create a new platform for medical monitoring. Many patients in the hospital are not monitored continuously and the medical monitors that we have now (ECG, pulse oximetry, blood pressure cuffs) require the patient to we wired or attached to a monitor. Dr. Wallace is developing a remote, non-contact patient monitor that relies on machine vision to continuously monitor patients. The monitor is designed to reduce morbidity and mortality by identifying patient deterioration prior to cardiac or respiratory arrest.

Art Wallace, M.D, Ph.D is a cardiac anesthesiologist, professor and vice-chairman of anesthesiology and perioperative care at the University of California San Francisco, and Chief of Anesthesia at the San Francisco VA Medical Center. Dr Wallace has developed medications, surgical procedures, medical devices, and medical informatics software.

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